High-dose biotin in progressive multiple sclerosis: A prospective study of 178 patients in routine clinical practice. Ann N Y Acad Sci 1985 447:389-92.Ĭouloume L, Barbin L, Leray E, et al. Biotin status and plasma glucose in diabetics. View abstract.Ĭoggeshall JC, Heggers JP, Robson MC, et al. Zinc aspartate, biotin, and clobetasol propionate in the treatment of alopecia areata in childhood. View abstract.Ĭamacho FM, Garcia-Hernandez MJ. Biochemical Hyperthyroidism in a Newborn Baby Caused by Assay Interaction from Biotin Intake. View abstract.īülow Pedersen I, Laurberg P. Relapses During High-Dose Biotin Treatment in Progressive Multiple Sclerosis: a Case-Crossover and Propensity Score-Adjusted Prospective Cohort. View abstract.īranger P, Parienti JJ, Derache N, Kassis N, Assouad R, Maillart E, Defer G. A Single 10?mg Oral Dose of Biotin Interferes with Thyroid Function Tests. View abstract.īiscolla RPM, Chiamolera MI, Kanashiro I, Maciel RMB, Vieira JGH. Misdiagnosis of Graves' disease with apparent severe hyperthyroidism in a patient taking biotin megadoses. Effects of biotin on pyruvate carboxylase, acetyl-CoA carboxylase, propionyl-CoA carboxylase, and markers for glucose and lipid homeostasis in type 2 diabetic patients and nondiabetic subjects. View abstract.īaez-Saldana A, Zendejas-Ruiz I, Revilla-Monsalve C, et al. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes. View abstract.Īlbarracin C, Fuqua B, Evans JL, Goldfine ID. Biotin-responsive basal ganglia disease maps to 2q36.3 and is due to mutations in SLC19A3. S., Jr., Slaugenhaupt, S., Gillis, T., MacDonald, M. Identification of biotin sulfone, bisnorbiotin methyl ketone, and tetranorbiotin-l-sulfoxide in human urine. Biliary excretion of biotin and biotin metabolites is quantitatively minor in rats and pigs. Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans. Current trends in the treatment of infantile spasms. PRELIMINARY OBSERVATIONS ON "EGG WHITE INJURY" IN MAN AND ITS CURE WITH A BIOTIN CONCENTRATE. Observations on the "egg white injury" in man and its cure with biotin concentrate. Inheritable biotin-treatable disorders and associated phenomena. Vitamin transport and homeostasis in mammalian brain: focus on Vitamins B and E. Depletion and repletion of biotinyl enzymes in liver of biotin-deficient rats: evidence of a biotin storage system. Sedel, F., Lyon-Caen, O., and Saudubray, J. Most multivitamins contain low doses of biotin, which are unlikely to interfere with blood tests. You may need to stop taking biotin before your blood test. Tell your doctor if you are taking biotin supplements, especially if you are having lab tests done. This might lead to missed or incorrect diagnoses. Biotin can cause falsely high or falsely low test results. Laboratory tests: Taking biotin supplements might interfere with the results of many different blood lab tests.
Smoking: People who smoke might have low biotin levels and may need a biotin supplement. Kidney dialysis: People receiving kidney dialysis might have low levels of biotin and may need a biotin supplement. An inherited condition in which the body cannot process biotin (biotinidase deficiency): People with this condition might have low levels of biotin and may need a biotin supplement.
It's been used safely in doses of 5-25 mcg daily. Pregnancy and breast-feeding: Biotin is likely safe when used in recommended amounts during pregnancy and breast-feeding.Ĭhildren: Biotin is likely safe when taken by mouth. When applied to the skin: Biotin is likely safe for most people when applied in cosmetic products that contain up to 0.6% biotin.
But it is more commonly used in lower doses of 2.5 mg daily. When taken by mouth: Biotin is likely safe for most people when taken in doses up to 300 mg daily for up to 6 months.
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